Interspecific character of the Müllerian-inhibiting substance: action of the human fetal testis, ovary and adrenal of the fetal rat Müllerian duct in organ culture.

Interspecific character of the Müllerian-inhibiting substance: action of the human fetal testis, ovary and adrenal of the fetal rat Müllerian duct in organ culture.
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苗勒管抑制物质的种间特征:器官培养中胎鼠苗勒管的人胎儿睾丸、卵巢和肾上腺的作用。

DOI:
10.1210/jcem-32-3-404
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发表时间:
1971
期刊:
The Journal of clinical endocrinology and metabolism
影响因子:
--
通讯作者:
N. Josso
N. Josso
中科院分区:
--
文献类型:
--
作者:
N. Josso

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摘要 将14.5天龄的胎鼠生殖道在无性腺的情况下取出,并与来自妊娠前半期获取的胎儿的人睾丸、卵巢或肾上腺一起置于器官培养中。胎鼠睾丸组织,无论其年龄如何,都能抑制大鼠的苗勒氏管;卵巢和肾上腺组织则不能。对这些发现的意义进行了讨论。
ABSTRACT Reproductive tracts of 14½-day-old fetal rats were explanted without gonads and placed in organ culture with human testes, ovaries or adrenals from fetuses obtained in the first half of pregnancy. Fetal testicular tissue, irrespective of its age, inhibited the rat mullerian ducts; ovarian and adrenal tissue did not. The significance of these findings is discussed.