Supercritical CO(2 )extraction, structural analysis and bioactivity of polysaccharide from Grifola frondosa
Supercritical CO(2 )extraction, structural analysis and bioactivity of polysaccharide from Grifola frondosa
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DOI:
10.1016/j.jfca.2021.104067
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发表时间:
2021
期刊:
影响因子:
--
通讯作者:
Yimin Xie
中科院分区:
文献类型:
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作者:
Houkuan Zhao;Xianyong Wei;Yimin Xie
Polysaccharide was extracted from Grifola frondosa with supercritical CO2 technology. The optimum extraction .conditions for the highest yield were determined by Box-Behnken design: the pressure was 34.5Mpa, the .extraction temperature was 36.7 ℃, the extraction time was 116.3 min and the ratio of entrainer to raw material .was 2.86 mL/g, to give a polysaccharide yield of 4.61 %. The polysaccharide from G. frondosa was purified with .ionic liquid. The polysaccharide was characterised as a predominantly heteropolysaccharide composed of .different monosaccharides with a β - type structure. The anti-tumour and antibacterial experiments on the .polysaccharide in vitro showed that the polysaccharide had marked anticancer and antibacterial effects.