Normal and abnormal pulmonary ventilation: Visualization at hyperpolarized He-3 MR imaging
Normal and abnormal pulmonary ventilation: Visualization at hyperpolarized He-3 MR imaging
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DOI：
10.1148/radiology.201.2.8888259
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发表时间：
1996-11-01
期刊：
影响因子：
19.7
通讯作者：
Thelen, M
中科院分区：
文献类型：
--
作者：
Kauczor, HU;Hofmann, D;Thelen, M
为了评估三维快速低角度激发（FLASH）序列氦-3磁共振（MR）成像的可行性，5名健康志愿者和5名肺部疾病患者吸入He-3气体（体积300 mt;压力3 x 10（5）Pa;通过最佳泵送极化高达45%）。所有屏气检查（22 - 42秒）均成功完成。正常通气tvas表现为均匀的高信号，病变表现为引起缺损，阻塞性肺疾病表现为严重的不均匀信号。
To assess the feasibility of helium-3 magnetic resonance (MR) imaging with a three-dimensional fast low-angle shot (FLASH) sequence, He-3 gas (volume, 300 mt; pressure, 3 x 10(5) Pa; polarized up to 45% by means of optimal pumping) was inhaled by five healthy volunteers and five patients with pulmonary diseases. All breath-hold examinations (22 - 42 seconds) were completed successfully. Normal ventilation tvas depicted with homogeneous high signal intensity, lesions were depicted as causing defects, and obstructive lung disease was depicted with severely inhomogeneous signal intensity.