Murine microvideo endoscopy of the colonic microcirculation
Murine microvideo endoscopy of the colonic microcirculation
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DOI：
10.1016/j.jss.2006.12.005
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发表时间：
2007-09-01
影响因子：
2.2
通讯作者：
Mentzer, Steven J.
中科院分区：
文献类型：
--
作者：
Ravnic, Dino J.;Konerding, Moritz A.;Mentzer, Steven J.
在过去，小动物模型中的自然孔口内窥镜检查受到仪器尺寸和光学性能的限制。在这份报告中，我们探讨了使用最近开发的显微视频内窥镜系统来评估结肠微循环的可行性。使用急性结肠炎的小鼠模型，显微视频内窥镜有助于绘制炎症的地形图以及识别微循环中的相关结构。我们的结论是，自然腔道内镜是一种有用的方法，微创纵向评估结肠粘膜微循环。(c)2007年爱思唯尔公司All rights reserved.
Natural orifice endoscopy in small animal models has been limited in the past by instrument size and optical performance. In this report, we investigate the feasibility of using a recently developed microvideo endoscopy system to evaluate the colon microcirculation. Using a murine model of acute colitis, microvideo endoscopy was useful in mapping the topography of inflammation as well as identifying relevant structures in the microcirculation. We conclude that natural orifice endoscopy is a useful method for the minimally invasive longitudinal assessment of the colonic mucosal microcirculation. (c) 2007 Elsevier Inc. All rights reserved.