The biofilm matrix
The biofilm matrix
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DOI：
10.1038/nrmicro2415
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发表时间：
2003-04-01
期刊：
影响因子：
2.7
通讯作者：
Allison, DG
中科院分区：
文献类型：
--
作者：
Allison, DG
细胞外基质是所有生物膜的复杂且极其重要的组分，为附着的群体提供建筑结构和机械稳定性。基质由细胞、水和分泌/释放的细胞外大分子组成。此外，在基质中可以发现一系列酶和调节活性。这些不同的组成部分和活动有可能相互作用，从而在矩阵中创造一系列当地环境，作为一个功能性的联合体共存。基质结构还受到许多外在因素的影响，包括营养物质和气体水平的波动以及流体剪切力。总之，这些内在和外在因素联合收割机为附着和包膜的细胞产生动态的、异质的微环境。
The extracellular matrix is a complex and extremely important component of all biofilms, providing architectural structure and mechanical stability to the attached population. The matrix is composed of cells, water and secreted/released extracellular macromolecules. In addition, a range of enzymic and regulatory activities can be found within the matrix. Together, these different components and activities are likely to interact and in so doing create a series of local environments within the matrix which co-exist as a functional consortium. The matrix architecture is also subject to a number of extrinsic factors, including fluctuations in nutrient and gaseous levels and fluid shear. Together, these intrinsic and extrinsic factors combine to produce a dynamic, heterogeneous microenvironment for the attached and enveloped cells.