Wavelet-based spectrum analysis of sacral skin blood flow response to alternating pressure
Wavelet-based spectrum analysis of sacral skin blood flow response to alternating pressure
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DOI：
10.1016/j.apmr.2007.07.046
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发表时间：
2008-01-01
影响因子：
4.3
通讯作者：
Karg, Patricia
中科院分区：
文献类型：
--
作者：
Jan, Yih-Kuen;Brienza, David M.;Karg, Patricia
目的：通过对皮肤血流（SBF）振荡的小波分析，深入了解与交变压力相关的生理机制，并确定交变压力的应用是否会诱导肌源性反应，从而与恒定负荷相比增强SBF。设计：重复测量设计。设置：大学研究实验室。参与者：健康的年轻成年人（N=10; 5名男性，5名女性;平均年龄+/-标准差，30.0 +/-3.1岁）。（4个5 min的循环，60 mmHg或3 mmHg），并在骶骨上方皮肤上以30 mmHg恒定负荷20分钟。主要结果测量：用激光多普勒血流计测量骶骨对交变压力和恒定负荷的SBF反应。SBF振荡的基于小波的频谱分析用于评估潜在的生理机制，包括内皮相关的代谢（.008.结果：与恒定负荷相比，交变压力刺激受压软组织骶骨SBF增加（P
Objectives: To provide insight into the physiologic mechanisms associated with alternating pressure, using wavelet analysis of skin blood flow (SBF) oscillations, and to determine whether the application of alternating pressure induces myogenic responses, thereby enhancing SBF as compared with constant loading.Design: Repeated- measures design.Setting: University research laboratory.Participants: Healthy, Young adults (N=10; 5 men, 5 women; mean age +/- standard deviation, 30.0 +/- 3.1y).Intervention: Alternating pressure for 20 minutes (four 5-min cycles with either 60mmHg or 3mmHg) and constant loading for 20 minutes at 30mmHg on the skin over the sacrum.Main Outcome Measures: A laser Doppler flowmeter was used to measure sacral SBF response to both alternating pressure and constant loading. Wavelet-based spectrum analysis of SBF oscillations was used to assess underlying physiologic mechanisms including endothelium-related metabolic (.008.-02Hz), neurogenic (.02-.05Hz), and myogenic (.05-.15Hz) controls.Results: Alternating pressure stimulated an increase in sacral SBF of compressed soft tissues as compared with constant loading (P