[Bickerstaff brainstem encephalitis: epidemiology, diagnosis, and therapy].
[Bickerstaff brainstem encephalitis: epidemiology, diagnosis, and therapy].
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[比克斯塔夫脑干脑炎：流行病学、诊断和治疗]。
DOI：
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发表时间：
2013
期刊：
影响因子：
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通讯作者：
M. Koga
中科院分区：
文献类型：
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作者：
M. Koga
作者回顾了Bickerstaff脑干脑炎（BBE）的流行病学和临床方面的数据的基础上，从全国范围内的调查，这是计划在2006年和2009年之间的日本人口。在日本，每年BBE的发病率粗略估计为100例，占脑干脑炎的43%，相当于格林-巴利综合征发病率的6.8%。BBE包括典型和非典型病例，典型BBE具有与Fisher综合征相似的神经学和血清学特征，且恢复良好，而非典型BBE的特点是恢复延迟，抗GQ 1b抗体阴性，CSF和脑MRI异常，可能有其他病因。
The author reviewed the epidemiological and clinical aspects of Bickerstaff brainstem encephalitis (BBE) based on the data from the nationwide survey, which was planned in Japanese population between 2006 and 2009. Annual BBE onset was roughly estimated as 100 cases in Japan, which accounted for 43% of brainstem encephalitis, and corresponded to 6.8% of Guillain-Barré syndrome incidence. BBE consisted of typical and atypical cases, and typical BBE had the similar neurological and serological features to Fisher syndrome as well as with good recovery, whereas atypical BBE was characterized by delayed recovery, negative anti-GQ1b antibodies, and abnormal CSF and brain MRI findings with possible other pathogeneses.