Efficient Synthesis of Water-Soluble Alkyl-bis(m-sulfonated-phenyl)- and Dialkyl-(m-sulfonated-phenyl)-phosphines and Their Evaluation in Rhodium-Catalyzed Hydrogenation of Maleic Acid in Water
Efficient Synthesis of Water-Soluble Alkyl-bis(m-sulfonated-phenyl)- and Dialkyl-(m-sulfonated-phenyl)-phosphines and Their Evaluation in Rhodium-Catalyzed Hydrogenation of Maleic Acid in Water
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DOI：
10.1021/om800570r
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发表时间：
2009-03-09
期刊：
影响因子：
2.8
通讯作者：
Horvath, Istvan T.
中科院分区：
文献类型：
--
作者：
Mika, Laszlo T.;Orha, Laszlo;Horvath, Istvan T.
P-31 NMR和pH测量在二苯基烷基膦磺化后三异辛胺辅助的水/有机分离和纯化步骤中的联合应用（Ph 2 PR; R = Me，n-Bu）和苯基-二烷基-膦（PhPR 2; R = Me，n-Bu）导致制备水溶性烷基-双（间-磺化-苯基）-（C6 H 4-m-SO 3 Na）（2）PR; R = Me，n-Bu）和二烷基-（间-磺化-苯基）-（C6 H 4-m-SO 3 Na）PR 2; R = Me，n-Bu）膦在小于0.5%氧化膦存在下的反应。当每个铑原子使用2当量的水溶性膦时，通过使用这些膦，可以观察到对马来酸氢化的移动频率没有显著影响。
The combined application of P-31 NMR and pH measurements during the tri-isooctylamine-assisted aqueous/organic separation and purification steps after the sulfonation of diphenyl-alkyl-phosphines (Ph2PR; R = Me, n-Bu) and phenyl-dialkyl-phosphines (PhPR2; R = Me, n-Bu) resulted in the preparation of water-soluble alkyl-bis(m-sulfonated-phenyl)-(C6H4-m-SO3Na)(2)PR; R = Me, n-Bu) and dialkyl-(m-sulfonated-phenyl)- (C6H4-m-SO3Na)PR2; R = Me, n-Bu) phosphines in the presence of less than 0.5% phosphine oxides. When 2 equiv of the water-soluble phosphines were used per rhodium atom, no significant effect on the tu mover frequency of the hydrogenation of maleic acid can be observed by using these phosphines.