Measurement of tissue optical properties in the context of tissue optical clearing
Measurement of tissue optical properties in the context of tissue optical clearing
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DOI：
10.1117/1.jbo.23.9.091416
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发表时间：
2018-09-01
影响因子：
3.5
通讯作者：
Tuchin, Valery V.
中科院分区：
文献类型：
--
作者：
Bashkatov, Alexey N.;Berezin, Kirill V.;Tuchin, Valery V.
当今，动态发展的光学（光子）技术在医学中发挥着越来越大的作用。它们在诊断、手术和治疗中的充分和有效实施需要关于人体组织（包括皮肤）光学特性的可靠数据。本文综述了近年来组织光学特性的测量和控制方面的研究成果。报告的问题包括对生物组织的光学特性和光学清除（OC）方法在糖尿病并发症监测和血管和微循环可视化中的应用的功效的简要回顾，使用了许多光学成像技术，包括光谱、光学相干断层扫描、偏振和斑点成像技术。本文还讨论了皮肤浸没式有机碳的分子模型和脂肪组织浸没式有机碳加热及光动力处理的具体技术。(C) 2018年中国光学仪器工程师学会（SPIE）
Nowadays, dynamically developing optical (photonic) technologies play an ever-increasing role in medicine. Their adequate and effective implementation in diagnostics, surgery, and therapy needs reliable data on optical properties of human tissues, including skin. This paper presents an overview of recent results on the measurements and control of tissue optical properties. The issues reported comprise a brief review of optical properties of biological tissues and efficacy of optical clearing (OC) method in application to monitoring of diabetic complications and visualization of blood vessels and microcirculation using a number of optical imaging technologies, including spectroscopic, optical coherence tomography, and polarization-and speckle-based ones. Molecular modeling of immersion OC of skin and specific technique of OC of adipose tissue by its heating and photodynamic treatment are also discussed. (C) 2018 Society of Photo-Optical Instrumentation Engineers (SPIE)