Coagulation and wound repair during COVID-19.
Coagulation and wound repair during COVID-19.
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DOI：
10.1016/j.healun.2021.06.006
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发表时间：
2021-10
期刊：
影响因子：
--
通讯作者：
Gralinski LE
中科院分区：
文献类型：
--
作者：
Menachery VD;Gralinski LE
While COVID-19 is best known as a respiratory infection, SARS-CoV-2 causes systemic disease manifestations including coagulopathies. Both dysregulated extracellular matrix remodeling pathways and circulating coagulation proteins are hallmarks of severe COVID-19 and often continue after the resolution of acute infection. Coagulation proteins have proven effective as biomarkers for severe disease and anticoagulants are a mainstay of COVID-19 therapeutics in hospitalized patients. While much knowledge has been gained about the role of clotting pathway activation in COVID-19, much remains to be elucidated in this complex network of signaling pathways.
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