Genetic Testing Awareness and Attitudes among Latinos: Exploring Shared Perceptions and Gender-Based Differences.
Genetic Testing Awareness and Attitudes among Latinos: Exploring Shared Perceptions and Gender-Based Differences.
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DOI：
10.1159/000441552
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发表时间：
2016
影响因子：
1.7
通讯作者：
Hay JL
中科院分区：
文献类型：
--
作者：
Hamilton JG;Shuk E;Arniella G;González CJ;Gold GS;Gany F;Robson ME;Hay JL
拉丁美洲人的观点很少在基因组研究中得到检验，他们可能面临错过基因组医学好处的风险。为了探索这种可能性，我们对纽约市文化适应程度较低的拉美裔人对基因检测的认识和态度进行了定性研究。我们进行了四个焦点小组（讲英语的男性，n=7；讲西班牙语的男性，n=5；讲英语的女性，n=13；讲西班牙语的女性，n=13），通过对基因检测的一般讨论，以及对皮肤癌风险的基因检测的假设描述，来探索影响采用新创新的因素。通过对焦点小组文本的归纳主题文本分析，我们的多学科团队确定了知识和态度中的主题；沟通和信息来源；预期的反应;可能增加采用率的因素；以及采用基因检测的障碍。具体而言，大多数参与者对基因检测的目的和这些检测提供的信息表示一定程度的不确定，很少在社交网络中与其他人讨论基因检测，并对基因信息的滥用和可能产生的不良情绪反应表示关切。然而，参与者也表达了对接受皮肤癌基因检测的高度兴趣，并认为接受可操作的健康信息是考虑进行检测的主要原因。在感知到的测试障碍方面出现了基于性别的差异。结果强调了未来干预措施可以针对的信念和障碍，以帮助确保拉丁美洲人充分了解和获得基因组医学进展。
Latinos, whose views are infrequently examined in genomic research, may be at risk of missing out on the benefits of genomic medicine. To explore this possibility, we conducted a qualitative study of awareness and attitudes about genetic testing among Latinos with lower acculturation in New York City. We conducted four focus groups (English-speaking men, n=7; Spanish-speaking men, n=5; English-speaking women, n=13; and Spanish-speaking women, n=13) to explore factors that influence the adoption of new innovations through the discussion of genetic testing in general, and a hypothetical vignette describing a genetic test for skin cancer risk, in particular. Through inductive thematic text analysis of focus group transcripts, our multidisciplinary team identified themes within knowledge and attitudes; communication and sources of information; anticipated responses; factors that may increase adoption; and barriers to adoption of genetic testing. Specifically, a majority of participants expressed some degree of uncertainty regarding the purpose of genetic tests and information these tests provide, rarely discussed genetic testing with others in their social networks, and expressed concerns about the misuse of and possible adverse emotional responses to genetic information. However, participants also expressed high levels of interest in receiving a skin cancer genetic test in response to the vignette, and believed that receiving actionable health information was a primary reason to consider testing. Gender-based differences in perceived barriers to testing emerged. Results highlight beliefs and barriers that future interventions could target to help ensure that Latinos have adequate understanding of and access to genomic medicine advances.