MORPHOLOGICAL AND HISTOCHEMICAL STUDY OF TRICHURIS-SUIS (SCHRANK, 1788) WITH SPECIAL REFERENCE TO HOST-PARASITE RELATIONSHIP
MORPHOLOGICAL AND HISTOCHEMICAL STUDY OF TRICHURIS-SUIS (SCHRANK, 1788) WITH SPECIAL REFERENCE TO HOST-PARASITE RELATIONSHIP
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DOI：
10.1017/s0031182000041202
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发表时间：
1970-01-01
期刊：
影响因子：
2.4
通讯作者：
JENKINS, T
中科院分区：
文献类型：
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作者：
JENKINS, T
猪鞭毛虫的成虫能够通过形成一个隧道状的结构来与宿主的组织建立密切的联系，该结构覆盖了一段线状的食道区域。最前面的口腔末端和更结实的后方区域没有被覆盖，自由地躺在盲肠的管腔内。附壁通道由宿主粘膜细胞和杯状细胞分泌物组成，并对其可能的构建方式进行了讨论。没有直接参与隧道形成的宿主组织似乎没有受到寄生虫的存在的伤害。因此，猪毛滴虫在自然条件下并不是一种严重的病原体。已有研究表明，毛状突食管区的特征结构，如菌带和刺突小体，在代谢上是活跃的。前者以起源于皮下的柱状突起的形式穿透层状角质层。每个皮下柱代表一个腺细胞或杆状细胞，显示出酶活性，如酸性磷酸酶、非特异性酯酶、葡萄糖-6-磷酸酶、琥珀酸脱氢酶、细胞色素氧化酶和β-d-葡萄糖苷酶。讨论了它在宿主-寄生虫界面和鞭虫新陈代谢中的可能功能。层状角质层是蛋白质和酶惰性的。腺体活动也显示在毛细血管样的食道周围的组织小体上。这一证据证实了早先的观点，即组织小体是一系列食管腺。尽管细菌带可能参与营养吸收，但已获得的证据表明，这是通过口腔进行的，这有利于摄取在食道中检测到的粘液物质。这可能会受到存在于食道和组织小体中的酶的初步水解。
Adult forms of the pig whipworm, T. suis, are able to establish intimate contact with the host's tissues by the formation of a tunnel-like construction which covers a section of the thread-like oesophageal region. The extreme anterior oral end and the stouter posterior region are not covered and lie free in the lumen of the caecum. The attachment tunnel is composed of host mucosal cells and goblet cell secretion and its possible mode of construction is discussed. Host tissue not directly involved in tunnel formation appears unharmed by the presence of the parasite. T. suis is therefore not a serious pathogen under natural conditions.It has been demonstrated that characteristic structures of the trichuroid oesophageal region, e.g. bacillary band and stichosome are metabolically active. The former penetrates the layered cuticle in the form of columnar protrusions originating in the hypodermis. Each hypodermal column represents a gland cell or bacifiary cell, which displays enzymic activity, e.g. acid phosphatase, non-specific esterase, glucose-6-phosphatase, succinate dehydrogenase, cytochrome oxidase and β-d-glucosidase. Its possible function at the host-parasite interface and in the metabolism of the whipworm is discussed. The layered cuticle is proteinaceous and enzymically inert.Glandular activity is also displayed by the stichosome surrounding the capillary-like oesophagus. This evidence confirms earlier suggestions that the stichosome is a series of oesophageal glands.Although the bacillary band may be involved in nutrient uptake the evidence obtained indicates that this is via the mouth which is favourably placed for the ingestion of mucoid material which was detected in the oesophagus. This may be subjected to preliminary hydrolysis by the enzymes present in the oesophagus and stichosome.