Body Composition and Survival in Stable Coronary Heart Disease Impact of Lean Mass Index and Body Fat in the "Obesity Paradox"

Body Composition and Survival in Stable Coronary Heart Disease Impact of Lean Mass Index and Body Fat in the "Obesity Paradox"
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DOI:
10.1016/j.jacc.2012.05.037
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发表时间:
2012-10-09
影响因子:
24
通讯作者:
Milani, Richard V.
Milani, Richard V.
中科院分区:
医学1区
文献类型:
--
作者:
Lavie, Carl J.;De Schutter, Alban;Milani, Richard V.

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目的探讨瘦体重指数(LMI)和体脂(BF)对冠心病(CHD)患者生存的影响。背景:在冠心病患者中,肥胖与预后之间存在负相关关系(“肥胖悖论”),这一关系被用体重指数来定义身体成分的局限性所解释。方法我们研究了连续570例接受心脏康复治疗的CHD患者,将其分为低BF组(女性为35%)和低BF组(女性为低BF组)。
Objectives Our goal was to determine the impact of lean mass index (LMI) and body fat (BF) on survival in patients with coronary heart disease (CHD).Background An inverse relationship between obesity and prognosis has been demonstrated (the "obesity paradox") in CHD, which has been explained by limitations in the use of body mass index in defining body composition.Methods We studied 570 consecutive patients with CHD who were referred to cardiac rehabilitation, stratified as Low (35% in women) BF and as Low (