Direct detection of the mercury-nitrogen bond in the thymine-HgII-thymine base-pair with 199Hg NMR spectroscopy
Direct detection of the mercury-nitrogen bond in the thymine-HgII-thymine base-pair with 199Hg NMR spectroscopy
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DOI：
10.1039/c5cc02423d
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发表时间：
2015-01-01
影响因子：
4.9
通讯作者：
Tanaka, Yoshiyuki
中科院分区：
文献类型：
--
作者：
Dairaku, Takenori;Furuita, Kyoko;Tanaka, Yoshiyuki
我们观察到Hg-Ⅱ介导的胸腺嘧啶-胸腺嘧啶碱基对（T-Hg-II-T）中的1-键Hg-199-N-15 J偶联（（1）J（Hg-199，N-15）= 1050 Hz）。这是第一个典型的sp（2）-氮原子的大J（Hg-199，N-15），它可以作为N-汞化化合物的灵敏结构探针和N-汞化的直接证据。
We have observed the 1-bond Hg-199-N-15 J-coupling ((1)J(Hg-199,N-15) = 1050 Hz) within the Hg-II-mediated thymine-thymine base pair (T-Hg-II-T). This strikingly large (1)J(Hg-199,N-15) is the first one for canonical sp(2)-nitrogen atoms, which can be a sensitive structure-probe of N-mercurated compounds and a direct evidence for N-mercuration.