Fractionation sensitivity and equivalent doses. Commenting on the editorial by Glimelius
Fractionation sensitivity and equivalent doses. Commenting on the editorial by Glimelius
复制标题
分次敏感性和等效剂量。
DOI：
10.1080/02841860701261576
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发表时间：
2007
期刊：
影响因子：
3.1
通讯作者：
A. Courdi
中科院分区：
文献类型：
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作者：
A. Courdi
我饶有兴趣地阅读了Glimelius [1]的社论，评论了布鲁克斯等人[2]关于直肠癌分割的论文。表I中有一些错误和不确定性。1.该表的标题是“生物等效剂量”。表中给出的数值为BED，即“生物学有效剂量”，而非生物学等效剂量。生物等效剂量是指相当于经典分次给药的剂量，每次2戈伊。同样的评论也适用于布鲁克斯的论文，表I。读者可能会对这两个词感到困惑。下文给出了一个来自表I的晚期效应的例子。
I have read with interest the Editorial by Glimelius [1], commenting on the paper by Brooks et al. [2] about fractionation in rectal cancer. There are some mistakes as well as some uncertainties in Table I. 1. The title of the table is ‘‘Biological equivalent doses’’. Values given in the table are BED, that is ‘‘Biologically effective dose’’, not biologically equivalent doses. Biologically equivalent doses are doses equivalent to classical fractionation given with 2 Gy per fraction. The same remark applies to Brooks paper, Table I. Readers may tend to be confused between the two terms. An example is given below for late effects, derived from Table I.