Impulsivity and history of drug dependence

Impulsivity and history of drug dependence
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DOI:
10.1016/s0376-8716(98)00023-4
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发表时间:
1998-04-01
影响因子:
4.2
通讯作者:
Cherek, DR
Cherek, DR
中科院分区:
医学2区
文献类型:
--
作者:
Allen, TJ;Moeller, FG;Cherek, DR

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使用行为和自我报告测量,对 32 名有药物依赖史 (DRUG +) 的受试者和 26 名无药物使用史 (DRUG -) 的受试者之间的冲动性进行了对比。假设是药物+组比药物组更冲动。在问卷中提出的情况下,药物+组的受试者自我报告比药物组更容易冲动。在涉及较小的中间奖励和较大但延迟的奖励之间进行选择的行为范式中,药物+受试者更频繁地选择冲动选项,但这些差异并不显着。药物+组和药物组在较大奖励的平均延迟间隔上确实存在差异,这表明对于较大奖励的容忍较长延迟的能力较差。较大奖励的延迟间隔的频率分布表明,药物+受试者更有可能维持非常短的间隔,而不太可能维持较长的间隔。 (C) 1998 Elsevier Science Ireland Ltd. 保留所有权利。
Impulsivity was contrasted between 32 subjects with a history of drug-dependence (DRUG +) and 26 subjects with no drug use history (DRUG -) using both behavioral and self-report measures. The hypothesis was that the DRUG + group would be more impulsive than the DRUG-group. Subjects in the DRUG + group self-reported more of a tendency toward impulsivity than the DRUG-group in the situations posed in questionnaires. In the behavioural paradigm involving a choice between a smaller intermediate reward and a larger but delayed reward, DRUG + subjects selected the impulsive option more often, but these differences were not significant. The DRUG + and DRUG-groups did differ on the mean delay interval for the larger reward, indicating less ability to tolerate longer delays for the larger reward. A frequency distribution of delay intervals for the larger reward indicated that DRUG + subjects were more likely to maintain very short intervals and less likely to maintain longer intervals. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.