A novel simian immunodeficiency virus isolated from a Schmidt's guenon (Cercopithecus ascanius schmidti).
A novel simian immunodeficiency virus isolated from a Schmidt's guenon (Cercopithecus ascanius schmidti).
复制标题
从施密特氏猴（Cercopithecus ascanius schmidti）中分离出一种新型猿猴免疫缺陷病毒。
DOI：
10.1099/vir.0.19427-0
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发表时间：
2004
期刊：
影响因子：
--
通讯作者：
J. Heeney
中科院分区：
文献类型：
--
作者：
E. Verschoor;Z. Fagrouch;I. Bontjer;H. Niphuis;J. Heeney
从当地动物园饲养的施密特猿猴（Cercopithecus ascanius schmidti）中鉴定出一种新型猿类免疫缺陷病毒（SIV）。在常规血清学筛查与SIVmac抗原交叉反应的抗体时检测到病毒感染。使用INNO-LIA HIV确认试验确认感染免疫缺陷病毒。利用从印迹血块中分离的DNA，扩增并测序了1895 nt部分pol序列。系统发育分析表明，这种被命名为SIVschm的病毒与从大点鼻猴中分离出来的SIVgsn有着遥远的关系，是迄今为止发现的最具多样性的siv之一。
A novel simian immunodeficiency virus (SIV) was characterized from a Schmidt's guenon (Cercopithecus ascanius schmidti), which was housed in a local zoo. The virus infection was detected during a routine serological screening for antibodies that were cross-reactive with SIVmac antigens. Infection with an immunodeficiency virus was confirmed using an INNO-LIA HIV Confirmation assay. Using DNA isolated from a blot clot, a 1895 nt partial pol sequence was amplified and sequenced. Phylogenetic analysis showed that this virus, designated SIVschm, shares a distant relationship with SIVgsn, isolated from greater spot-nosed monkeys, and is one of the most divergent SIVs identified to date.
影响因子：
56.9
作者：
Korber, B;Muldoon, M;Bhattacharya, T
通讯作者：
Bhattacharya, T