Prevention of lipid loss from hair by surface and internal modification
Prevention of lipid loss from hair by surface and internal modification
复制标题
通过表面和内部改性防止头发脂质流失
DOI：
10.1038/s41598-019-46370-x
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发表时间：
2019
影响因子：
4.6
通讯作者：
Sang
中科院分区：
文献类型：
--
作者：
Sang;J. H. Lim;S. Son;Julia Choi;N. Kang;Sang
在日常洗涤过程中，表面活性剂对头发的脂质损失有巨大的影响。本研究旨在了解头发与表面活性剂接触后脂质的损失，并开发一种防止脂质损失的方法。脂质水平的变化取决于脂质的相对疏水性。我们在此提出，脂质水平的变化可以通过两种修饰来保护。在脂肪酸和胆固醇（A组）的情况下，在用表面活性剂洗涤后，原始毛发与用高电荷聚合物表面改性的毛发之间的浓度差高22至32%，而角鲨烯和蜡酯（B组）响应于表面活性剂的损失甚至在表面改性后仍然发生。在用碳二亚胺反应进行内部改性处理的头发中，B组中的脂质比未处理的头发多52.0 - 81.3%。最后，通过表面活性剂处理的表面和内部改性，成功地保护了不同类型的脂质。这项研究将是了解表面活性剂损害包括头发在内的组织的脂质屏障的机制和建立防御屏障的策略的基础。
Surfactants during routine washing have a tremendous effect on lipid loss from hair. This study aims to understand the loss of lipids from hair upon contact with surfactants and develop a way to prevent the lipid loss. The change in lipid levels depends on the relative hydrophobicity of the lipid. We herein propose that the change in lipid levels can be protected by two modifications. In the case of fatty acids and cholesterol (group A), the concentration difference between virgin hair versus surface modified hair with highly charged polymer was 22 to 32% higher after washing with surfactants while the loss of squalene and wax esters (group B) in response to surfactants still occurred even after the surface modification. In the hair treated by internal modification with the carbodiimide reaction, 52.0 to 81.3% more lipids in group B were prevented than in the untreated hair. Finally, different types of lipids were successfully protected by surface and internal modifications from the surfactant treatment. This study will be the basis for understanding the mechanisms by which surfactants damage the lipid barrier of tissues including hair and for establishing strategies to defend the barrier.