Cancer risk among lung transplant recipients with cystic fibrosis.
Cancer risk among lung transplant recipients with cystic fibrosis.
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DOI：
10.1016/j.jcf.2016.07.011
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发表时间：
2017-01
期刊：
影响因子：
--
通讯作者：
Engels EA
中科院分区：
文献类型：
--
作者：
Fink AK;Yanik EL;Marshall BC;Wilschanski M;Lynch CF;Austin AA;Copeland G;Safaeian M;Engels EA
Previous studies demonstrated increased digestive tract cancers among individuals with cystic fibrosis (CF), particularly among lung transplant recipients. We describe cancer incidence among CF and non-CF lung recipients. We used data from the US transplant registry and 16 cancer registries. Standardized incidence ratios (SIRs) compared cancer incidence to the general population, and competing risk methods were used for the cumulative incidence of colorectal cancer. We evaluated 10,179 lung recipients (1,681 with CF). Risk was more strongly increased in CF recipients than non-CF recipients for overall cancer (SIR 9.9 vs. 2.7) and multiple cancers including colorectal cancer (24.2 vs. 1.7), esophageal cancer (56.3 vs. 1.3), and non-Hodgkin lymphoma (61.8 vs. 9.4). At five years post-transplant, colorectal cancer was diagnosed in 0.3% of CF recipients aged <50 at transplant and 6.4% aged ≥50. CF recipients have increased risk for colorectal cancer, suggesting a need for enhanced screening.
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影响因子：
120.7
作者：
Engels, Eric A.;Pfeiffer, Ruth M.;Fraumeni, Joseph F., Jr.;Kasiske, Bertram L.;Israni, Ajay K.;Snyder, Jon J.;Wolfe, Robert A.;Goodrich, Nathan P.;Bayakly, A. Rana;Clarke, Christina A.;Copeland, Glenn;Finch, Jack L.;Fleissner, Mary Lou;Goodman, Marc T.;Kahn, Amy;Koch, Lori;Lynch, Charles F.;Madeleine, Margaret M.;Pawlish, Karen;Rao, Chandrika;Williams, Melanie A.;Castenson, David;Curry, Michael;Parsons, Ruth;Fant, Gregory;Lin, Monica
通讯作者：
Lin, Monica
DOI：
10.1111/ajt.13549
发表时间：
2016-03
期刊：
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
影响因子：
--
作者：
Safaeian M;Robbins HA;Berndt SI;Lynch CF;Fraumeni JF Jr;Engels EA
通讯作者：
Engels EA
影响因子：
6.4
作者：
Johannesson, Marie;Askling, Johan;Bahmanyar, Shahram
通讯作者：
Bahmanyar, Shahram
影响因子：
10.3
作者：
Maisonneuve, Patrick;Marshall, Bruce C.;Lowenfels, Albert B.
通讯作者：
Lowenfels, Albert B.
影响因子：
10.3
作者：
Maisonneuve, P;FitzSimmons, SC;Lowenfels, AB
通讯作者：
Lowenfels, AB