Postprandial lipemia: reliability in an epidemiologic field study.
Postprandial lipemia: reliability in an epidemiologic field study.
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餐后脂血症：流行病学现场研究的可靠性。
DOI：
10.1093/oxfordjournals.aje.a116531
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发表时间：
1992
影响因子：
5
通讯作者：
Patsch,W
中科院分区：
文献类型：
--
作者：
Brown,SA;Chambless,LE;Sharrett,AR;GottoJr,AM;Patsch,W
来自北卡罗来纳州福赛斯县和马里兰州华盛顿县社区动脉粥样硬化风险研究现场中心的 10 名受试者在 1988 年 9 月至 1989 年 2 月的 10 天内进行了两次脂肪耐受性测试，以确定餐后脂血症标记物的再现性。两次就诊之间的空腹平均血脂、脂蛋白和载脂蛋白没有发现显着差异。在测试餐后 3.5 小时和 9.0 小时测量全血浆中的餐后甘油三酯和视黄酯棕榈酸酯。访问之间这些分析的平均水平没有显着差异。 9.0 小时重复访视之间的甘油三酯相关性 (r= 0.87) 比空腹样本 (r= 0.67) 或 3.5 小时 (r= 0.69) 时的相关性更强。 3.5 小时时的平均血浆棕榈酸视黄酯水平比 9.0 小时时高 15%。 9.0 小时时棕榈酸视黄酯重复测量值的相关性 (r= 0.94) 比 3.5 小时时的重复测量值 (r= 0.79) 强得多。总之，餐后 9.0 小时甘油三酯和视黄醇棕榈酸酯水平测量的可靠性估计与空腹总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、高密度脂蛋白 3 胆固醇的血脂测量一样强，并且餐后甘油三酯测量均超过空腹甘油三酯测量 (r = 0.67)。Am J Epidemiol1992； 136：538–45
Ten subjects from the Forsyth Country, North Carolina, and Washington Country, Maryland, field centers in the Atherosclerosis Risk in Communities Study had two fat tolerance tests within a 10-day period from September 1988 to February 1989 to determine the reproducibility of markers for postprandial lipemia. No significant differences between visits were found in fasting mean plasma lipids, lipoproteins, and apolipoproteins. Postprandial triglycerides and retinyl palmitate were measured at 3.5 and 9.0 hours after the test meal in whole plasma. There were no significant differences in the mean levels of these analysis between visits. The correlation of triglycerides between repeat visits at 9.0 hours (r= 0.87) was stronger than in fasting samples (r= 0.67) or at 3.5 hours (r= 0.69). The mean plasma retinyl palmitate level at 3.5 hours was 15% higher than at the 9.0-hour level. The correlation of repeat measures of retinyl palmitate at 9.0 hours (r= 0.94) was much stronger than at 3.5 hours (r= 0.79). In conclusion, estimates of reliability in postprandial measurements of 9.0-hour triglycer-ides and retinyl palmitate levels were as strong as fasting lipid measurements of total cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol, high density lipoprotein3 cholesterol, and both postprandial triglyceride measurements exceeded that of fasting triglyceride (r= 0.67).Am J Epidemiol1992; 136: 538–45