Chlamydia trachomatis and Neisseria gonorrhoeae Transmission from the Oropharynx to the Urethra among Men Who Have Sex with Men
Chlamydia trachomatis and Neisseria gonorrhoeae Transmission from the Oropharynx to the Urethra among Men Who Have Sex with Men
复制标题
DOI：
10.1086/648427
复制
发表时间：
2009-12-15
影响因子：
11.8
通讯作者：
Klausner, Jeffrey D.
中科院分区：
文献类型：
--
作者：
Bernstein, Kyle T.;Stephens, Sally C.;Klausner, Jeffrey D.
背景。关于沙眼衣原体和淋病奈瑟菌从口咽传播到尿道的风险的数据有限。我们检查了 2007 年在旧金山城市诊所（加利福尼亚州旧金山）就诊的男男性行为者 (MSM) 的尿道沙眼衣原体和淋病奈瑟菌阳性情况。方法。所有在旧金山市诊所（旧金山唯一的市性传播疾病诊所）寻求治疗的患者都接受了临床医生进行的标准化访谈。我们估计了 2007 年 MSM 就诊的 2 组尿道沙眼衣原体和淋病奈瑟菌阳性率：(1) 报告其唯一尿道暴露是在过去 3 个月内接受口交的男性；(2) 报告在过去 3 个月内进行过无保护插入肛交的男性。此外，还评估了尿道沙眼衣原体和淋病奈瑟菌阳性率，并根据人类免疫缺陷病毒感染状况、泌尿生殖系统症状史以及患者是否接触过患有衣原体或淋病的性伴侣进行分层。结果。在仅接受口交的 MSM 中，尿道沙眼衣原体和淋病奈瑟菌阳性率分别为 4.8% 和 4.1%。这些阳性率估计值与报告无保护插入肛交的 MSM 中发现的阳性率相似。结论。更全面地了解沙眼衣原体和淋病奈瑟菌从口咽到尿道传播的风险将有助于为预防和筛查计划提供信息。
Background. Limited data exist on the risk of Chlamydia trachomatis and Neisseria gonorrhoeae transmission from oropharynx to urethra. We examined urethral C. trachomatis and N. gonorrhoeae positivity among men who have sex with men (MSM) seen at San Francisco City Clinic (San Francisco, CA) during 2007.Methods. All patients who sought care at the San Francisco City Clinic (the only municipal sexually transmitted disease clinic in San Francisco) received a standardized interview conducted by clinicians. We estimated urethral C. trachomatis and N. gonorrhoeae positivity for 2 groups of visits by MSM who visited during 2007: (1) men who reported their only urethral exposure was receiving fellatio in the previous 3 months and (2) men who reported unprotected insertive anal sex in the previous 3 months. Additionally, urethral C. trachomatis and N. gonorrhoeae positivity was estimated, stratified by human immunodeficiency virus infection status, urogenital symptom history, and whether the patient had been a contact to a sex partner with either chlamydia or gonorrhea.Results. Among MSM who reported only receiving fellatio, urethral C. trachomatis and N. gonorrhoeae positivity were 4.8% and 4.1%, respectively. These positivity estimates were similar to positivity found among MSM who reported unprotected insertive anal sex.Conclusions. A more complete understanding of the risks of transmission of C. trachomatis and N. gonorrhoeae from oropharynx to urethra will help inform prevention and screening programs.