A model of bovine tuberculosis control in domesticated cattle herds

A model of bovine tuberculosis control in domesticated cattle herds
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驯养牛群中牛结核病控制模型

DOI:
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发表时间:
1997
期刊:
Proceedings of the Royal Society of London. Series B: Biological Sciences
影响因子:
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通讯作者:
T. Ryan
T. Ryan
中科院分区:
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文献类型:
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作者:
R. Kao;M. Roberts;T. Ryan

文献摘要

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控制家畜疾病的典型策略包括定期进行田间试验和对受感染的畜群进行检疫。这可以防止疾病传播到畜群之外,而屠宰患病动物可以消除畜群内的感染。研究了牛结核病(Tb)控制模型,该模型包括“测试和屠宰”结合牛群隔离和疫苗接种。畜群状态由表示畜群隔离持续时间的积分方程表示。以新西兰结核病现状为例,讨论了结核病疫苗接种策略。对现有管理战略的推断表明,需要一种效力高于96%的疫苗,在六年内达到结核病目标水平的95%。这些结果表明,疫苗接种和病媒控制的互补策略可能比单独接种更有希望。
A typical strategy for disease control in domesticated animals involves regular field tests and quarantine of infected herds. This prevents disease spread beyond the herd, while slaughter of diseased animals removes the infection from within the herd. A model of bovine tuberculosis (Tb) control in cattle is examined, which includes ‘test and slaughter’ combined with herd isolation and vaccination. Herd status is represented by an integral equation expressing the duration of herd isolation. The current Tb situation in New Zealand is used as an example, and vaccination strategy discussed. Extrapolation of existing management strategies indicate that a vaccine of efficacy greater than 96 per cent would be required, reaching 95per cent of target Tb levels within six years. These results suggest that a complementary strategy of vaccination and vector control may be more promising than vaccination alone.