Identification of repellent odorants to the body louse, Pediculus humanus corporis, in clove essential oil.
Identification of repellent odorants to the body louse, Pediculus humanus corporis, in clove essential oil.
复制标题
丁香精油中对体虱（Pediculus humanus corporis）的驱避气味剂的鉴定。
DOI：
10.1007/s00436-016-4905-9
复制
发表时间：
2016
期刊：
影响因子：
--
通讯作者：
Kanzaki R.
中科院分区：
文献类型：
--
作者：
Iwamatsu T.;Miyamoto D.;Mitsuno H.;Yoshioka Y.;Fujii T.;Sakurai T.;Ishikawa Y.;Kanzaki R.
体虱的控制对人类的健康和福祉是一个重要的问题，因为体虱是斑疹伤寒、复发性热和战壕热等疾病的媒介。体虱对一些精油表现出回避行为，包括丁香精油。因此，含有丁香精油成分的气味物质可能在开发体虱驱避剂方面有潜在的用处。然而，从丁香精油中还没有鉴定出这种能在体虱中诱导回避行为的气味物质。在这里，我们建立了一种分析方法来评估体虱对特定气味的回避行为。体虱对丁香精油及其成分的行为分析表明，丁香精油的主要成分丁香酚对体虱有很强的驱避作用，而其他成分则不能诱导出明显的回避行为。丁香酚与其他结构上相关的气味物质的驱避效果的比较揭示了可能的部分对于避免体虱的影响是重要的。丁香酚与丁香精油的另一主要成分β-石竹烯联合使用，可增强丁香酚对体虱的驱避作用。我们得出结论，丁香酚和β-石竹烯的合成混合物是最有效的体虱驱避剂。这一发现将是有价值的，因为丁香酚作为体虱驱避剂的潜在用途。
The control of body lice is an important issue for human health and welfare because lice act as vectors of disease such as typhus, relapsing fever, and trench fever. Body lice exhibit avoidance behavior to some essential oils, including clove essential oil. Therefore, odorants containing clove essential oil components may potentially be useful in the development of repellents to body lice. However, such odorants that induce avoidance behavior in body lice have not yet been identified from clove essential oil. Here, we established an analysis method to evaluate the avoidance behavior of body lice to specific odorants. The behavioral analysis of the body lice in response to clove essential oil and its constituents revealed that eugenol, a major component of clove essential oil, has strong repellent effect on body lice, whereas the other components failed to induce obvious avoidance behavior. A comparison of the repellent effects of eugenol with those of other structurally related odorants revealed possible moieties that are important for the avoidance effects to body lice. The repellent effect of eugenol to body lice was enhanced by combining it with the other major component of clove essential oil, β-caryophyllene. We conclude that a synthetic blend of eugenol and β-caryophyllene is the most effective repellent to body lice. This finding will be valuable as the potential use of eugenol as body lice repellent.