Gas chromatography mass spectrometry of androstanolones as methyl oxime, tert-butyldimethylsilyl ether derivatives.
Gas chromatography mass spectrometry of androstanolones as methyl oxime, tert-butyldimethylsilyl ether derivatives.
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气相色谱质谱法测定雄甾烷酮作为甲基肟、叔丁基二甲基甲硅烷基醚衍生物。
DOI：
10.1002/bms.1200080309
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发表时间：
1981
期刊：
影响因子：
--
通讯作者：
A. Pike
中科院分区：
文献类型：
--
作者：
S. Gaskell;A. Pike
雄甾烷酮的甲基肟、叔丁基二甲基甲硅烷基衍生物在电子碰撞下的断裂强烈地受衍生化官能团的指导。几种主要的碎裂途径的相对重要性在位置异构体和立体异构体之间各不相同。[M-C4 H9]+的高分辨率选择离子监测和[M-C4 H9]+ [M-C4 H9-H（CH 3）2SiOH]+的亚稳峰监测均可用于高灵敏度分析。
The fragmentation of the methyl oxime, tert-butyldimethylsilyl derivatives of androstanolones under electron impact is strongly directed by the derivatized functional groups. The relative importance of the few major fragmentation pathways varies between positional isomers and stereoisomers. High resolution selected ion monitoring of [M—C4H9]+, and metastable peak monitoring of [M—C4H9]+ [M—C4H9—H(CH3)2SiOH]+, may both be used for high sensitivity analysis.