Predicting the development of diabetes in older adults - The derivation and validation of a prediction rule

Predicting the development of diabetes in older adults - The derivation and validation of a prediction rule
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DOI:
10.2337/diacare.28.2.404
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发表时间:
2005-02-01
期刊:
影响因子:
16.2
通讯作者:
Barrett-Connor, E
Barrett-Connor, E
中科院分区:
医学1区
文献类型:
--
作者:
Kanaya, AM;Fyr, CLW;Barrett-Connor, E

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目的 - 创建一个简单的预测规则,可以通过穿孔素以及攻击后 2 小时血浆葡萄糖 (PCPG) 测试来预测那些有糖尿病风险的人。我们在一个样本中创建了一条 0 预测规则,并在单独的队列中对糖尿病事件进行前瞻性验证。 研究设计和方法 - 使用 Rancho Bernardo 研究(年龄 67 +/- 11 岁)的数据进行横断面分析,使用空腹血浆非糖尿病参与者的人口统计、临床和实验室数据得出预测异常 PCPG 大于或等于 140 mg/dl 的 I 规则 葡萄糖 (FPG)
OBJECTIVE - To create a simple prediction rule that could perforin as well as the 2-h postchallenge plasma glucose (PCPG) test to predict those at risk for diabetes. We created a 0 prediction rule in one sample and prospectively validated it for incident diabetes in a separate cohort.RESEARCH DESIGN AND METHODS - A cross-sectional analysis with data from the Rancho Bernardo Study (age 67 +/- 11 years) to derive I rule predicting abnormal PCPG greater than or equal to140 mg/dl, using demographic, clinical, and laboratory data of nondiabetic participants with fasting plasma glucose (FPG)