Recruitment methods for united states Alzheimer disease prevention trials

Recruitment methods for united states Alzheimer disease prevention trials
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DOI:
10.1007/s12603-012-0011-6
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发表时间:
2012-04-01
影响因子:
5.8
通讯作者:
Schneider, L. S.
Schneider, L. S.
中科院分区:
医学3区
文献类型:
--
作者:
Schneider, L. S.

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阿尔茨海默病还没有有效的治疗方法或预防措施。进行的少数预防试验没有显示出药物的有效性;但是,先进的预防试验方法。我们回顾过去的招聘方法,讨论需要改进的地方。招募方法的改进可以提高准确证明有效药物功效的可能性。预防阿尔茨海默病的有效治疗方法有待发现和证明。
There are no substantially effective treatments or preventatives for Alzheimer disease. The few prevention trials that were undertaken did not shown efficacy for the drugs tested; but, nevertheless, advanced prevention trials methods. We review past recruitment methods and discuss areas for improvement. Improvements in recruitment methods can enhance the likelihood for accurately demonstrating the efficacy of an effective drug. Effective therapeutics to prevent AD await discovery and proof.