Fast vergence eye movements are disrupted in Parkinson's disease: A video-oculography study

Fast vergence eye movements are disrupted in Parkinson's disease: A video-oculography study
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DOI:
10.1016/j.parkreldis.2015.04.014
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发表时间:
2015-07-01
影响因子:
4.1
通讯作者:
Ruzicka, Evzen
Ruzicka, Evzen
中科院分区:
医学2区
文献类型:
--
作者:
Hanuska, Jaromir;Bonnet, Cecilia;Ruzicka, Evzen

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背景:近视力模糊是帕金森病(PD)患者常见的非运动性症状,但缺乏对会聚眼球运动(VEM)的详细描述。方法:对18例帕金森病患者和18例对照组进行会聚和发散检查。垂直平面和水平平面的VEM指标包括潜伏期、速度和准确性。结果:PD患者的收敛和发散潜伏期显著延长。此外,发散是缓慢和低节律的,而其他收敛指标与对照组相似。结论:我们为帕金森病患者的VEM障碍提供了证据。(C)2015爱思唯尔有限公司。保留所有权利。
Background: Blurred near vision is a common non-motor symptom in patients with Parkinson's disease (PD), however detailed characterization of vergence eye movements (VEM) is lacking.Methods: Convergence and divergence were examined in 18 patients with PD and 18 control subjects using infrared video-oculography. VEM metrics analyzed included latency, velocity and accuracy, in vertical and horizontal planes.Results: The latency of convergence and divergence was significantly increased in PD subjects. Additionally, divergence was slow and hypometric, while other convergence metrics were similar to controls.Conclusion: We provide evidence in favor of disrupted VEM in PD. (C) 2015 Elsevier Ltd. All rights reserved.