Intestinal ischemic manifestations of SARS-CoV-2: Results from the ABDOCOVID multicentre study.
Intestinal ischemic manifestations of SARS-CoV-2: Results from the ABDOCOVID multicentre study.
复制标题
DOI：
10.3748/wjg.v27.i32.5448
复制
发表时间：
2021-08-28
影响因子：
4.3
通讯作者：
Elli L
中科院分区：
文献类型：
--
作者：
Norsa L;Bonaffini PA;Caldato M;Bonifacio C;Sonzogni A;Indriolo A;Valle C;Furfaro F;Bonanomi A;Franco PN;Gori M;Smania V;Scaramella L;Forzenigo L;Vecchi M;Solbiati M;Costantino G;Danese S;D'Antiga L;Sironi S;Elli L
Intestinal ischemia has been described in case reports of patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (coronavirus disease 19, COVID-19). To define the clinical and histological, characteristics, as well as the outcome of ischemic gastrointestinal manifestations of SARS-CoV-2 infection. A structured retrospective collection was promoted among three tertiary referral centres during the first wave of the pandemic in northern Italy. Clinical, radiological, endoscopic and histological data of patients hospitalized for COVID-19 between March 1st and May 30th were reviewed. The diagnosis was established by consecutive analysis of all abdominal computed tomography (CT) scans performed. Among 2929 patients, 21 (0.7%) showed gastrointestinal ischemic manifestations either as presenting symptom or during hospitalization. Abdominal CT showed bowel distention in 6 patients while signs of colitis/enteritis in 12. Three patients presented thrombosis of main abdominal veins. Endoscopy, when feasible, confirmed the diagnosis (6 patients). Surgical resection was necessary in 4/21 patients. Histological tissue examination showed distinctive features of endothelial inflammation in the small bowel and colon. Median hospital stay was 9 d with a mortality rate of 39%. Gastrointestinal ischemia represents a rare manifestation of COVID-19. A high index of suspicion should lead to investigate this complication by CT scan, in the attempt to reduce its high mortality rate. Histology shows atypical feature of ischemia with important endotheliitis, probably linked to thrombotic microangiopathies.
登录
查看更多内容
影响因子：
168.9
作者：
Huang, Chaolin;Wang, Yeming;Cao, Bin
通讯作者：
Cao, Bin
影响因子：
29.4
作者：
Norsa, Lorenzo;Cosimo, Paola;Callegaro, Annapaola
通讯作者：
Callegaro, Annapaola
DOI：
10.4166/kjg.2020.76.3.164
发表时间：
2020-09-01
期刊：
KOREAN JOURNAL OF GASTROENTEROLOGY
影响因子：
--
作者：
Singh, Balraj;Mechineni, Ashesha;Bikkina, Mahesh
通讯作者：
Bikkina, Mahesh
影响因子：
19.7
作者：
Bhayana R;Som A;Li MD;Carey DE;Anderson MA;Blake MA;Catalano O;Gee MS;Hahn PF;Harisinghani M;Kilcoyne A;Lee SI;Mojtahed A;Pandharipande PV;Pierce TT;Rosman DA;Saini S;Samir AE;Simeone JF;Gervais DA;Velmahos G;Misdraji J;Kambadakone A
通讯作者：
Kambadakone A
74例伴有胃肠道症状的2019年冠状病毒感染症（COVID-19）病例的流行病学、临床和病毒学特征
影响因子：
24.5
作者：
Jin, Xi;Lian, Jiang-Shan;Yang, Yida
通讯作者：
Yang, Yida