Sexual function in men older than 50 years of age: Results from the health professionals follow-up study
Sexual function in men older than 50 years of age: Results from the health professionals follow-up study
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DOI：
10.7326/0003-4819-139-3-200308050-00005
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发表时间：
2003-08-05
影响因子：
39.2
通讯作者：
Rimm, EB
中科院分区：
文献类型：
--
作者：
Bacon, CG;Mittleman, MA;Rimm, EB
背景：尽管许多研究提供了特定情况下勃起功能障碍的数据，但很少有研究足够大，可以精确地检查特定年龄的患病率及其相关性。目的：描述年龄与50岁以上男性性功能的几个方面之间的关系。设计：前瞻性队列研究数据的横断面分析。背景：美国卫生专业人员。参与者：31 742名男性，年龄53至90岁。测量方法：2000年寄出的问卷询问了性功能、体力活动、体重、吸烟、婚姻状况、医疗状况和药物。自1986年以来，以前的两年一次的调查问卷询问了出生日期、酒精摄入量和其他健康信息。结果：排除前列腺癌患者后，前3个月勃起功能障碍的年龄标准化患病率为33%。性功能的许多方面（包括整体功能、欲望、性高潮和整体能力）在50岁以后急剧下降。体力活动与勃起功能障碍的风险较低相关（多变量相对风险，每周32.6代谢当量运动小时为0.7 [95% CI， 0.6至0.7]，每周0至2.7代谢当量运动小时为0.7），肥胖与较高的风险相关（相对风险，1.3 [CI， 1.2至1.4]）体重指数>28.7 kg/m(2) VS。
Background: Although many studies have provided data on erectile dysfunction in specific settings, few studies have been large enough to precisely examine age-specific prevalence and correlates.Objective: To describe the association between age and several aspects of sexual functioning in men older than 50 years of age.Design: Cross-sectional analysis of data from a prospective cohort study.Setting: U.S. health professionals. Participants: 31 742 men, age 53 to 90 years.Measurements: Questionnaires mailed in 2000 asked about sexual function, physical activity, body weight, smoking, marital status, medical conditions, and medications. Previous biennial questionnaires since 1986 asked about date of birth, alcohol intake, and other health information.Results: When men with prostate cancer were excluded, the age-standardized prevalence of erectile dysfunction in the previous 3 months was 33%. Many aspects of sexual function (including overall function, desire, orgasm, and overall ability) decreased sharply by decade after 50 years of age. Physical activity was associated with lower risk for erectile dysfunction (multivariable relative risk, 0.7 [95% CI, 0.6 to 0.7] for >32.6 metabolic equivalent hours of exercise per week vs. 0 to 2.7 metabolic equivalent hours of exercise per week), and obesity was associated with higher risk (relative risk, 1.3 [CI, 1.2 to 1.4] for body mass index >28.7 kg/m(2) VS.