New prenylated indole alkaloids from fungus Penicillium sp derived of mangrove soil sample
New prenylated indole alkaloids from fungus Penicillium sp derived of mangrove soil sample
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来自红树林土壤样品的真菌青霉属的新异戊二烯化吲哚生物碱
DOI：
10.1016/j.tet.2014.04.043
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发表时间：
2014-06-24
期刊：
影响因子：
2.1
通讯作者：
Liu, Yonghong
中科院分区：
文献类型：
--
作者：
Yang, Bin;Dong, Junde;Liu, Yonghong
从真菌青霉属（Penicillium sp.）中分离得到三种二异戊二烯化吲哚生物碱，mangrovamides A-C（1-3），具有双环[2.2.2]二氮杂辛烷核，并具有新的γ-甲基脯氨酸和异戊二烯衍生的二甲基γ-吡喃酮官能团，其是从红树林土壤样品中分离的。其结构经核磁共振、X-射线衍射和圆二色谱等方法鉴定。提出了这些化合物可能的生物合成途径。(C)2014爱思唯尔有限公司版权所有。
Three diprenylated indole alkaloids, mangrovamides A-C (1-3), featured a bicyclo [2.2.2] diazaoctane core and possessed a novel gamma-methyl proline and isoprene derived dimethyl gamma-pyrone functionalities hitherto unknown among the family of paraherquamides, were isolated from the fungus Penicillium sp., which was separated from a mangrove soil sample. The structures were elucidated based on NMR, X-ray, and CD methods. The possible biosynthetic pathway of these compounds is proposed. (C) 2014 Elsevier Ltd. All rights reserved.