Mechanomorphogenic Films Formed via Interfacial Assembly of Fluorinated Amino Acids
Mechanomorphogenic Films Formed via Interfacial Assembly of Fluorinated Amino Acids
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DOI：
10.1002/adfm.202104223
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发表时间：
2021-06
影响因子：
19
通讯作者：
Janna N. Sloand;Tyler E. Culp;Nichole Wonderling;E. Gomez;Scott H. Medina
中科院分区：
文献类型：
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作者：
Janna N. Sloand;Tyler E. Culp;Nichole Wonderling;E. Gomez;Scott H. Medina
自然界已经进化出几种优雅的策略，将惰性构建块组织成适应性的超分子结构。其中最受青睐的是界面自组装，其中液-液连接的独特环境提供了不同于主体溶液的结构、动力学、热力学和化学性质。在这里，利用相反的氟-水界面来引导非正则的氟化氨基酸组装成结晶的机械形态形成膜。也就是说，这种策略赋予的纳米级秩序产生了自我修复材料，这种材料可以根据外部机械刺激改变其宏观形态。此外，与天然生物分子一样，有机氟氨基酸薄膜可以响应环境离子强度、pH和温度的变化而采用不同的第二和第三状态。补充的生物物理和生化研究被用来开发一个氨基酸包装的模型，以使这种生物响应行为合理化。最后，这些薄膜表现出选择性的渗透性，在捕获氟化合物的同时允许水的自由扩散。这些独特的能力被利用在该技术的示范应用中，以快速从受污染的水样中提取全氟烷基物质。对这些材料的持续探索将促进对界面模板化和氟驱动组装现象如何共同利用来设计适应性分子网络和生物的理解。
Nature has evolved several elegant strategies to organize inert building blocks into adaptive supramolecular structures. Favored among these is interfacial self‐assembly, where the unique environment of liquid–liquid junctions provides structural, kinetic, thermodynamic, and chemical properties that are distinct from the bulk solution. Here, antithetical fluorous–water interfaces are exploited to guide the assembly of non‐canonical fluorinated amino acids into crystalline mechanomorphogenic films. That is, the nanoscale order imparted by this strategy yields self‐healing materials that can alter their macro‐morphology depending on exogenous mechanical stimuli. Additionally, like natural biomolecules, organofluorine amino acid films respond to changes in environmental ionic strength, pH, and temperature to adopt varied secondary and tertiary states. Complementary biophysical and biochemical studies are used to develop a model of amino acid packing to rationalize this bioresponsive behavior. Finally, these films show selective permeability, capturing fluorous compounds while allowing the free diffusion of water. These unique capabilities are leveraged in an exemplary application of the technology to extract perfluoroalkyl substances from contaminated water samples rapidly. Continued exploration of these materials will advance the understanding of how interface‐templated and fluorine‐driven assembly phenomenon a can be co‐utilized to design adaptive molecular networks and living matter.