Acute toxicity of peracetic acid (PAA) formulations to Ichthyophthirius multifiliis theronts
Acute toxicity of peracetic acid (PAA) formulations to Ichthyophthirius multifiliis theronts
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DOI：
10.1007/s00436-009-1361-9
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发表时间：
2009-02
影响因子：
2
通讯作者：
D. Straus;T. Meinelt
中科院分区：
文献类型：
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作者：
D. Straus;T. Meinelt
过氧乙酸（PAA）是一种用于农业、食品加工和医疗设施的抗菌消毒剂。它最近被建议作为一种手段来控制感染ofIchthyophthirius multifiliis。本研究的目的是测定两种含4.5%和40% PAA的产品对I的急性毒性。来自两个地理上分离的分离株的多丝状体。将Theronts暴露于含有23°C地下水的96孔板中的PAA浓度。在4小时内观察到急性毒性。4.5% PAA产品4 h时两种分离株的半数致死浓度（LC 50）估计值无显著差异（0.146 vs 0.108 mg/l PAA），而40% PAA产品4 h LC 50之间存在统计学差异（0.274 vs 0.158 mg/l PAA）。这些结果表明PAA对I有毒性。multifiliistherons在低浓度和一个菌株是更耐这种化合物。
Peracetic acid (PAA) is an antimicrobial disinfectant used in agriculture, food processing, and medical facilities. It has recently been suggested as a means to control infestations ofIchthyophthirius multifiliis. The purpose of this study was to determine the acute toxicity of two products containing 4.5% and 40% PAA toI. multifiliistheronts from two geographically separate isolates. Theronts were exposed to concentrations of PAA in 96-well plates containing groundwater at 23°C. Acute toxicity was observed over a 4-h period. No significant difference in the median lethal concentration (LC50) estimates was evident between the two isolates at 4 h with the 4.5% PAA product (0.146 versus 0.108 mg/l PAA), while there was a statistical difference between the 4 h LC50with the 40% PAA product (0.274 versus 0.158 mg/l PAA). These results suggest that PAA is toxic toI. multifiliistheronts at low concentrations and that one of the isolates was more resistant to this compound.