Impact of HIV Infection on Diastolic Function and Left Ventricular Mass
Impact of HIV Infection on Diastolic Function and Left Ventricular Mass
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DOI：
10.1161/circheartfailure.109.854943
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发表时间：
2010-01-01
影响因子：
9.7
通讯作者：
Bolger, Ann F.
中科院分区：
文献类型：
--
作者：
Hsue, Priscilla Y.;Hunt, Peter W.;Bolger, Ann F.
背景-HIV感染者患心血管疾病的风险增加，但其潜在机制尚不清楚。本研究的目的是确定无症状的HIV感染者与HIV-uninfected individuals.Methods/Results-We之间的超声心动图异常的患病率进行了超声心动图在196 HIV感染的成年人和52名对照。根据美国超声心动图协会标准评估左心室射血分数、左心室质量（体表面积指数）和舒张功能。HIV感染者的左心室质量指数更高（HIV感染者为77.2 g/m2，对照组为66.5 g/m2，P
Background-Patients with HIV have increased risk for cardiovascular disease, but the underlying mechanisms remain unknown. The purpose of this study was to determine the prevalence of echocardiographic abnormalities among asymptomatic HIV-infected individuals compared with HIV-uninfected individuals.Methods/Results-We performed echocardiography in 196 HIV-infected adults and 52 controls. Left ventricular ejection fraction, left ventricular mass indexed to the body surface area, and diastolic function were assessed according to American Society of Echocardiography standards. Left ventricular mass index was higher in HIV-infected patients (77.2 g/m(2) in patients with HIV versus 66.5 g/m(2) in controls, P