Knee Arthritis Without Other Joint Symptoms in the Elderly With Seronegative Elderly Onset Rheumatoid Arthritis.
Knee Arthritis Without Other Joint Symptoms in the Elderly With Seronegative Elderly Onset Rheumatoid Arthritis.
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DOI：
10.2174/1874325001610010793
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发表时间：
2016
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Date R
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作者：
Mine T;Ihara K;Kawamura H;Kuriyama R;Date R
老年起病类风湿性关节炎（EORA）与年轻起病类风湿性关节炎（YORA）具有重要的临床区别。老年膝关节炎患者术前检查CRP升高、膝关节积液混浊时，应怀疑感染、结晶性关节炎或EORA。此外，如果全膝关节置换术（TKA）后关节肿胀和积液仍然存在，则应考虑TKA后感染、假体碎片相关性关节炎和EORA。然而，如果类风湿因子（RF）和抗环瓜氨酸肽抗体（ACPA）呈阴性，则难以诊断为EORA。鉴别诊断非常重要。
Elderly onset Rheumatoid arthritis (EORA) has important clinical distinctions when compared with younger onset RA (YORA). In knee arthritis of elderly patients, infection, crystal-induced arthritis or EORA should be suspected if elevation of CRP in the preoperative examination and turbid joint effusion in their knee joint are found. Furthermore, if joint swelling and effusion remain after performing total knee arthroplasty (TKA), the infection after TKA, implant debris-related arthritis and EORA should be considered. However, it is difficult to diagnose patients as EORA if Rheumatoid factor (RF) and anti-cyclic citrullinated peptide antibody (ACPA) are negative. The differential diagnosis is very important.