Convenient nomenclature of cysteine-rich polypeptide toxins from sea anemones
Convenient nomenclature of cysteine-rich polypeptide toxins from sea anemones
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DOI：
10.1016/j.peptides.2011.12.008
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发表时间：
2012-02-01
期刊：
影响因子：
3
通讯作者：
Grishin, Eugene
中科院分区：
文献类型：
--
作者：
Kozlov, Sergey;Grishin, Eugene
多肽毒素是天然毒液的主要成分。这些分子的研究取得了相当大的进展，导致了大量的结构相关的序列的测定。为了对新发现的分子进行分类，开发了一种用于命名肽毒素的合理命名法，该命名法考虑了毒素的生物活性、物种名称和多肽的结构特性。在此，我们建议修改这个命名为富含半胱氨酸的多肽毒素从海葵和描述11个新的多肽结构后推导出共同的数据库修订。(C)2011 Elsevier Inc. All rights reserved.
Polypeptide toxins are the main constituents of natural venoms. Considerable progress in the study of these molecules has resulted in the determination of a large number of structurally related sequences. To classify newly discovered molecules, a rational nomenclature for naming peptide toxins was developed, which takes into account toxin biological activity, the species name, and structural peculiarities of the polypeptide. Herein, we suggest modifications to this nomenclature for cysteine-rich polypeptide toxins from sea anemones and describe 11 novel polypeptide structures deduced after common database revision. (C) 2011 Elsevier Inc. All rights reserved.