CEREBRAL CORTICAL MICRO-FLUOROMETRY AT ISOSBESTIC WAVELENGTHS FOR CORRECTION OF VASCULAR ARTIFACT
CEREBRAL CORTICAL MICRO-FLUOROMETRY AT ISOSBESTIC WAVELENGTHS FOR CORRECTION OF VASCULAR ARTIFACT
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DOI：
10.1126/science.223243
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发表时间：
1979-01-01
期刊：
影响因子：
56.9
通讯作者：
PEARLSTEIN, RD
中科院分区：
文献类型：
--
作者：
KRAMER, RS;PEARLSTEIN, RD
显微荧光测量大脑皮质线粒体呼吸在体内被模糊的血流动力学和血氧伪影。等吸光度荧光法提供了适当的纠正这些血管现象，并允许同时评估线粒体烟酰胺腺嘌呤二核苷酸氧化还原状态，微循环容量和血红蛋白氧合。
Microfluorometric measurements of cerebral cortical mitochondrial respiration in vivo are obscured by hemodynamic and oximetric artifacts. Isosbestic fluorometry provides appropriate correction for these vascular phenomena and permits simultaneous evaluation of mitochondrial nicotinamide adenine dinucleotide redox state, microcirculatory volume, and hemoglobin oxygenation.