Passive valves based on hydrophobic microfluidics
Passive valves based on hydrophobic microfluidics
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DOI:
10.1016/s0924-4247(03)00363-7
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发表时间:
2003-11-15
影响因子:
4.6
通讯作者:
Xiong, HJ
中科院分区:
文献类型:
--
作者:
Feng, YY;Zhou, ZY;Xiong, HJ
Fluid-surface interactions can become dominant in microfluidics, which is a central technology in a number of miniaturized systems for chemical, biological and medical applications. In this paper, two kinds of hydrophobic valves in microfluidic applications were presented. One is based on special geometrical designs and chemical modification for silicon dioxide and glass microchannels. Silicon dioxide and Pyrex glass surfaces, which are hydrophilic originally, are modified with octadecyltrichlorosilane (OTS) self-assembled monolayers (SAMs) to be hydrophobic, with the contact angles up to similar to 102 and 103degrees, respectively, for water. The formation of OTS SAMs takes