Passive valves based on hydrophobic microfluidics

Passive valves based on hydrophobic microfluidics
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DOI:
10.1016/s0924-4247(03)00363-7
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发表时间:
2003-11-15
影响因子:
4.6
通讯作者:
Xiong, HJ
Xiong, HJ
中科院分区:
工程技术3区
文献类型:
--
作者:
Feng, YY;Zhou, ZY;Xiong, HJ

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流体 - 表面相互作用在微流体中可能变得占主导地位,微流体是许多用于化学、生物和医学应用的微型化系统中的一项核心技术。在本文中,介绍了微流体应用中的两种疏水阀。一种是基于对二氧化硅和玻璃微通道的特殊几何设计及化学改性。原本亲水的二氧化硅和派热克斯玻璃表面用十八烷基三氯硅烷(OTS)自组装单分子层(SAMs)进行改性以使其具有疏水性,对于水而言,接触角分别高达约102度和103度。OTS自组装单分子层的形成需要……
Fluid-surface interactions can become dominant in microfluidics, which is a central technology in a number of miniaturized systems for chemical, biological and medical applications. In this paper, two kinds of hydrophobic valves in microfluidic applications were presented. One is based on special geometrical designs and chemical modification for silicon dioxide and glass microchannels. Silicon dioxide and Pyrex glass surfaces, which are hydrophilic originally, are modified with octadecyltrichlorosilane (OTS) self-assembled monolayers (SAMs) to be hydrophobic, with the contact angles up to similar to 102 and 103degrees, respectively, for water. The formation of OTS SAMs takes