Occupational exposure to cleaning products and asthma in hospital workers
Occupational exposure to cleaning products and asthma in hospital workers
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DOI：
10.1136/oemed-2012-100826
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发表时间：
2012-12-01
影响因子：
4.9
通讯作者：
Le Moual, Nicole
中科院分区：
文献类型：
--
作者：
Dumas, Orianne;Donnay, Carole;Le Moual, Nicole
目的清洁用品可引起职业性哮喘，但有关具体暴露的信息很少。我们的目的是确定哮喘和职业暴露于清洁剂在医院workers.Methods进行了分析，在179（136名妇女）医院工作人员和参考人群的545名受试者（18-79岁）从法国病例对照和家族性哮喘的遗传学和环境的流行病学研究（2003-2007年）。使用三种方法估计清洁剂的暴露：自我报告、专家评估和哮喘特定工作暴露矩阵（JEM）。通过Logistic回归分析，按性别分层，调整年龄和吸烟状况，评估清洁产品和当前哮喘之间的关联。结果根据专家评估，55%的男性和81%的女性医院工作人员每周暴露于清洁/消毒任务（P
Objective Cleaning products may cause work-related asthma, but information regarding the specific exposures involved is scarce. We aimed to determine the associations between asthma and occupational exposure to cleaning agents in hospital workers.Methods Analyses were conducted in 179 (136 women) hospital workers and a reference population of 545 subjects (18-79 years) from the French case-control and familial Epidemiological study on the Genetics and Environment of Asthma (2003-2007). Exposures to cleaning agents were estimated using three methods: self-report, expert assessment and an asthma-specific job-exposure matrix (JEM). Associations between cleaning products and current asthma were evaluated by logistic regressions, stratified by sex and adjusted for age and smoking status.Results According to expert assessment, 55% of male and 81% of female hospital workers were exposed to cleaning/disinfecting tasks weekly (p