Dynamic three-dimensional imaging of the mitral valve and left ventricle by rapid sonomicrometry array localization
Dynamic three-dimensional imaging of the mitral valve and left ventricle by rapid sonomicrometry array localization
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DOI：
10.1016/s0022-5223(96)70056-9
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发表时间：
1996-09-01
影响因子：
6
通讯作者：
Edmunds, LH
中科院分区：
文献类型：
--
作者：
Gorman, JH;Gupta, KB;Edmunds, LH
目的，第一个目的是开发一种定量方法来跟踪二尖瓣的三维几何形状，第二个目的是确定体内二尖瓣的各种组件的复杂相互关系。方法和结果。在8只麻醉绵羊的心肺转流术之前和期间，将16个声测微传感器放置在二尖瓣环周围、两个乳头肌的尖端和基部、心室尖部、心室心外膜短轴上和前胸壁上，随后对动物进行了17次研究，再现了声测微阵列定位的推导弦长和三维坐标，研究了换能器信号的寿命、二尖瓣和左心室的动力学。距离测量的重现性平均为1.6%; Procrustes分析的三维阵列的坐标位置预测的平均误差为2.2毫米，持续时间的系列sonomicrometry阵列定位信号的范围在60和151天之间超声测微阵列定位显示二尖瓣环呈马鞍形，在二尖瓣终末前瓣口面积最小，收缩期不均匀，心尖下降，乳头肌缩短仅3.0 ~ 3.5mm，声测微阵列定位显示乳头肌传感器绕纵轴的不均匀扭转，并显示收缩期乳头肌基底朝向彼此旋转，结论。超声测微阵列定位图像标记实验动物的心室结构是高度可重复的，适合于连续观察。在绵羊中，该方法提供了关于二尖瓣和左心室结构在整个心动周期中的相互关系的独特的定量信息。
Objectives, The first objective was to develop a quantitative method for tracking the three-dimensional geometry of the mitral valve, The second was to determine the complex interrelationships of various components of the mitral valve in vivo. Methods and results. Sixteen sonomicrometry transducers were placed around the mitral valve anulus, at the tips and bases of both papillary muscles, at the ventricular apex, across the ventricular epicardial short axis, and on the anterior chest wall before and during cardiopulmonary bypass in eight anesthetized sheep, Animals were studied later on 17 occasions, Reproducibility of derived chord lengths and three-dimensional coordinates from sonomicrometry array localization, longevity of transducer signals, and the dynamics of the mitral valve and left ventricle were studied, Reproducibility of distance measurements averages 1.6%; Procrustes analysis of three-dimensional arrays of coordinate locations predicts an average error of 2.2 mm, Duration of serial sonomicrometry array localization signals ranges between 60 and 151 days (mean 114 days), Sonomicrometry array localization demonstrates the saddle-shaped mitral anulus, its minimal orifice area immediately before end-diastole, and uneven, apical descent during systole, Papillary muscles shorten only 3.0 to 3.5 mm, Sonomicrometry array localization demonstrates nonuniform torsion of papillary muscle transducers around a longitudinal axis and shows rotation of papillary muscular bases toward each other during systole, Conclusion. Tagging of ventricular structures in experimental animals by sonomicrometry array localization images is highly reproducible and suitable for serial observations, In sheep the method provides unique, quantitative information regarding the interrelationship of mitral valvular and left ventricular structures throughout the cardiac cycle.