Progress from CASP6 to CASP7

Progress from CASP6 to CASP7
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DOI:
10.1002/prot.21769
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发表时间:
2007-01-01
影响因子:
2.9
通讯作者:
Moult, John
Moult, John
中科院分区:
生物学4区
文献类型:
--
作者:
Kryshtafovych, Andriy;Fidelis, Krzysztof;Moult, John

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本文描述了提交给 CASP7 的三维结构模型的总体质量,并分析了自上次实验以来的进展,主要使用了早期分析中使用的测量方法。与 CASP6 相比,模型精度的改进不大,但有两个值得注意的进展。服务器性能已经接近人类的性能,并且最佳模型优于使用单个最佳模板结构的知识获得的目标的比例有了显着改善。
This article describes the general quality of models of three dimensional structure submitted to CASP7 and analyzes progress since the previous experiment, primarily using measures that were used in earlier analyses Overall. improvement in model accuracy compared to CASP6 is modest, but there are two developments of note. server performance has moved closer to that of humans, and there has been a significant improvement in the fraction of targets for which the best model is superior to that obtainable using knowledge of a single best template structure.