Peritoneal carcinomatosis of gastric origin: A population-based study on incidence, survival and risk factors

Peritoneal carcinomatosis of gastric origin: A population-based study on incidence, survival and risk factors
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DOI:
10.1002/ijc.28373
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发表时间:
2014-02-01
影响因子:
6.4
通讯作者:
de Hingh, Ignace H.
de Hingh, Ignace H.
中科院分区:
医学1区
文献类型:
--
作者:
Thomassen, Irene;van Gestel, Yvette R.;de Hingh, Ignace H.

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腹膜癌病(PC)是导致胃癌患者发病和死亡的重要原因。本研究的目的是为胃源性PC的发生率、危险因素和预后提供可靠的基于人群的数据。纳入了1995至2011年间埃因霍温癌症登记处地区所有被诊断为胃癌的患者。计算发病率和存活率,并用多因素Logistic回归分析确定腹膜癌病的危险因素。总共有5,220名患者被诊断为胃癌,其中2,029人(39%)出现转移疾病。706名患者(14%)存在PC,其中491名患者(9%)PC是唯一的转移部位。更年轻的年龄(
Peritoneal carcinomatosis (PC) is an important cause of morbidity and mortality among patients with gastric cancer. The aim of the current study was to provide reliable population-based data on the incidence, risk factors and prognosis of PC of gastric origin. All patients diagnosed with gastric cancer in the area of the Eindhoven Cancer Registry between 1995 and 2011 were included. Incidence and survival were computed and risk factors for peritoneal carcinomatosis were determined using multivariate logistic regression analysis. In total, 5,220 patients were diagnosed with gastric cancer, of whom 2,029 (39%) presented with metastatic disease. PC was present in 706 patients (14%) of whom 491 patients (9%) had PC as the only metastatic site. Younger age (