Derivation of inter-lamellar behaviour of the intervertebral disc annulus.
Derivation of inter-lamellar behaviour of the intervertebral disc annulus.
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DOI：
10.1016/j.jmbbm.2015.03.028
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发表时间：
2015-08
影响因子：
3.9
通讯作者：
Wilcox RK
中科院分区：
文献类型：
--
作者：
Mengoni M;Luxmoore BJ;Wijayathunga VN;Jones AC;Broom ND;Wilcox RK
椎间盘纤维环的层间连接已被证明会影响计算模型中整体椎间盘行为的预测。采用实验和计算相结合的方法，研究了径向载荷条件下椎间盘环的层间机械行为。从四个冷冻绵羊胸腰椎的 12 个椎间盘中解剖出 27 个前纤维环样本。根据样本在纤维环内的径向来源对样本进行分组。进行标准拉伸测试。此外，还使用显微镜下的微拉伸测试来观察片层的位移和层间连接。与实验协议相匹配的有限元模型是根据样本特定的几何形状和边界条件（假定已知的层状行为）开发的。使用优化过程来导出每组的界面刚度值。线性内聚界面的假设用于模拟层间连接的行为。从优化过程中得出的界面刚度值始终高于相应的层状值。外环的界面刚度值比内环高43%至75%。界面的切向刚度值比每组内的正常刚度值高 6% 到 39%，与其他研究人员报告的值相似。这些结果反映了层间连接性的复杂纤维性质，并为连续水平上层间行为的表示提供了值。
The inter-lamellar connectivity of the annulus fibrosus in the intervertebral disc has been shown to affect the prediction of the overall disc behaviour in computational models. Using a combined experimental and computational approach, the inter-lamellar mechanical behaviour of the disc annulus was investigated under conditions of radial loading. Twenty-seven specimens of anterior annulus fibrosus were dissected from 12 discs taken from four frozen ovine thoracolumbar spines. Specimens were grouped depending on their radial provenance within the annulus fibrosus. Standard tensile tests were performed. In addition, micro-tensile tests under microscopy were used to observe the displacement of the lamellae and inter-lamellar connections. Finite elements models matching the experimental protocols were developed with specimen-specific geometries and boundary conditions assuming a known lamellar behaviour. An optimisation process was used to derive the interface stiffness values for each group. The assumption of a linear cohesive interface was used to model the behaviour of the inter-lamellar connectivity. The interface stiffness values derived from the optimisation process were consistently higher than the corresponding lamellar values. The interface stiffness values of the outer annulus were from 43% to 75% higher than those of the inner annulus. Tangential stiffness values for the interface were from 6% to 39% higher than normal stiffness values within each group and similar to values reported by other investigators. These results reflect the intricate fibrous nature of the inter-lamellar connectivity and provide values for the representation of the inter-lamellar behaviour at a continuum level.
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DOI：
10.1016/j.jmbbm.2009.09.002
发表时间：
2010-02-01
影响因子：
3.9
作者：
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DOI：
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发表时间：
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影响因子：
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作者：
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