Experimental pathogenicity of four opportunist Fusarium species in a murine model
Experimental pathogenicity of four opportunist Fusarium species in a murine model
复制标题
DOI：
10.1099/00222615-48-4-363
复制
发表时间：
1999-04-01
影响因子：
3
通讯作者：
Guarro, J
中科院分区：
文献类型：
--
作者：
Mayayo, E;Pujol, I;Guarro, J
采用小鼠免疫活性动物模型，对属于人类最常见的四种镰刀菌属（F. solani，F.尖孢F. verticillioides和F. proliferatum）。将每种镰刀菌分离物的5 × 10（6）分生孢子/小鼠的接种物注射到小鼠尾部的侧静脉中以产生全身感染，枯落物是毒性最强的物种;所测定的该物种的五个菌株导致所有试验动物的死亡。
A murine model with immunocompetent animals was used in a comparative study of experimental pathogenicity of 13 isolates belonging to the four most frequent pathogenic species of Fusarium in man (F. solani, F. oxysporum, F. verticillioides and F. proliferatum). Inocula of 5 x 10(6) conidia/mouse of each isolate of Fusarium were injected into a lateral vein of the tail of the mice to produce a systemic infection, K solani was the most virulent species; the five strains of this species assayed caused the death of all the animals tested in