Diagnostic mammography performance and race: outcomes in Black and White women.
Diagnostic mammography performance and race: outcomes in Black and White women.
复制标题
诊断性乳房X光检查表现和种族：黑人和白人女性的结果。
DOI：
10.1002/cncr.21550
复制
发表时间：
2005
期刊：
影响因子：
--
通讯作者：
Gill,KarminderS
中科院分区：
文献类型：
--
作者：
Yankaskas,BonnieC;Gill,KarminderS
BACKGROUNDA previous study compared the performance (sensitivity, specificity, positive predictive value, and cancer detection rate) of screening mammography in Black and White women. No study, to the authors' knowledge, has evaluated the difference in the performance of diagnostic mammography between Black and White women.METHODSUnivariate analysis was used to evaluate differences in characteristics and cancers between Black and White women. Stratified and adjusted logistic regression analyses were used to test the association of Black and White race with performance measures of diagnostic mammography.RESULTSThe sensitivity of diagnostic mammography was higher (91% vs. 84%) and specificity was lower (86% vs. 90%) among Black women compared with White women. After controlling for age, density, self‐reported breast problems, and previous mammography, sensitivity was significantly higher (odds ratio [OR] = 1.82, 95% confidence interval [CI] = 1.22–2.80) and specificity was significantly lower (OR = 0.75, 95% CI = 0.70–0.81) among Black women. The crude cancer detection rate of mammography was higher for Black women (42.6/1000) than for White women (31.0/1000) and Black women had a higher proportion of cancers that were > 2.0 cm (57.4% vs. 46.2%) that were more often poorly differentiated (61.7% vs. 49.3%) and were more often estrogen‐receptor and progesterone‐receptor negative.CONCLUSIONSBlack women have lower specificity of diagnostic mammography and, consequently, more unnecessary workups than White women. Black women have higher sensitivity of diagnostic mammography, with cancers that are larger and more advanced than White women. Delay in responding to signs and symptoms would explain the size and later stage. However, more research is needed to understand the biologic differences of breast cancer characteristics between Black and White women. Cancer 2005. © 2005 American Cancer Society.
