HANGOVER EFFECTS THE MORNING AFTER MARIJUANA SMOKING
HANGOVER EFFECTS THE MORNING AFTER MARIJUANA SMOKING
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DOI：
10.1016/0376-8716(85)90002-x
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发表时间：
1985-01-01
影响因子：
4.2
通讯作者：
SCHUSTER, CR
中科院分区：
文献类型：
--
作者：
CHAIT, LD;FISCHMAN, MW;SCHUSTER, CR
13名男性大麻吸烟者参与了一项研究，以确定第二天早上吸食大麻是否会导致可测量的主观或其他行为影响。受试者根据标准化吸烟法吸食活性(2.9%)或安慰剂(0.0%)大麻香烟。通过测量吸烟前后呼出的空气CO水平来监测吸烟量。急性地，活跃的大麻引起心率、CO水平、主观效应的各种测量以及卡片分类、自由回忆和时间产生的行为任务的显著改变。当第二天早上重复测试电池时(.apprx.吸食后9h)，两种主观效能量表和时间生产任务在吸食大麻后均有显著变化，但安慰剂未见显著变化。这些明显的“宿醉”效应与大麻的急性效应不同。吸食大麻显然会在吸烟后第二天产生残留(宿醉)效应。这些影响的确切性质和程度及其实际影响仍有待确定。
Thirteen male marihuana smokers participated in a study to determine whether marihuana smoked in the evening would result in measurable subjective or other behavioral effects the following morning. Subjects smoked either active (2.9% .DELTA.9THC [delta-9-tetrahydrocannabinol]) or placebo (0.0% .DELTA.9THC) marihuana cigarettes according to a standardized smoking regimen. Smoke inhalation was monitored by measuring expired air CO levels before and after smoking. Acutely, active marihuana produced significant changes in heart rate, CO level, various measures of subjective effects and behavioral tasks of card sorting, free recall and time production. When the test battery was repeated the following morning (.apprx. 9 h after smoking), significant changes were observed on 2 subjective effects scales and on the time production task after active, but not placebo, marihuana. These apparent ''hangover'' effects were different from the acute effects of marihuana. Marihuana smoking can apparently produce residual (hangover) effects the day after smoking. The precise nature and extent of these effects, as well as their practical implications, remain to be determined.