Newer-Generation Ultrathin Strut Drug-Eluting Stents Versus Older Second-Generation Thicker Strut Drug-Eluting Stents for Coronary Artery Disease Meta-Analysis of Randomized Trials
Newer-Generation Ultrathin Strut Drug-Eluting Stents Versus Older Second-Generation Thicker Strut Drug-Eluting Stents for Coronary Artery Disease Meta-Analysis of Randomized Trials
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DOI：
10.1161/circulationaha.118.034456
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发表时间：
2018-11-13
期刊：
影响因子：
37.8
通讯作者：
Stone, Gregg W.
中科院分区：
文献类型：
--
作者：
Bangalore, Sripal;Toklu, Bora;Stone, Gregg W.
背景：当代第二代药物洗脱支架(DES)在接受经皮冠状动脉介入治疗的患者中与早期支架相比具有更好的有效性和安全性，部分原因与其支架较薄有关。与较老的第二代较厚的支架相比，新一代超薄支架是否会进一步改善临床结果尚不清楚。方法：我们在PubMed、Embase和Cochrane Central Register of Control Trials中搜索随机临床试验，比较新一代超薄支架(定义为支架厚度)
BACKGROUND: Contemporary second-generation drug-eluting stents (DES) have superior efficacy and safety in comparison with early-generation stents in patients undergoing percutaneous coronary intervention, in part, related to their thinner struts. Whether newer-generation ultrathin DES further improve clinical outcomes in comparison with older second-generation thicker strut DES is unknown.METHODS: We searched PubMed, Embase, and Cochrane Central Register of Controlled Trials for randomized clinical trials that compared newer-generation ultrathin strut DES (defined as strut thickness