Surgical relief of causalgia with an artificial nerve guide tube: Successful surgical treatment of causalgia (Complex Regional Pain Syndrome Type II) by in situ tissue engineering with a polyglycolic acid-collagen tube

Surgical relief of causalgia with an artificial nerve guide tube: Successful surgical treatment of causalgia (Complex Regional Pain Syndrome Type II) by in situ tissue engineering with a polyglycolic acid-collagen tube
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DOI:
10.1016/j.pain.2005.05.033
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发表时间:
2005-10-01
期刊:
影响因子:
7.4
通讯作者:
Nakamura, T
Nakamura, T
中科院分区:
医学1区
文献类型:
--
作者:
Inada, Y;Morimoto, S;Nakamura, T

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两名患者与痛觉超敏和手指挛缩相关的头痛手术治疗与生物可吸收的神经导管由聚乙醇酸和胶原蛋白制成:手指神经的损伤段被切除,并产生的差距(25和36毫米)与管桥接。在这两个病例中,在受损神经上发现了神经瘤,并发现了许多发芽的分支。术后6个月内,疼痛消失,手指运动功能恢复。客观地确定了1年9个月的功能恢复。两名患者恢复了手指的完全使用,分别长达24个月和18个月没有不适。自从1864年第一次描述了卡劳痛以来,一直没有明确的治疗方法来治疗这种顽固性烧灼痛。我们的经验表明,至少某些类型的头痛可以通过手术成功解决。(c)2005年国际疼痛研究协会。Elsevier B.V.出版,保留所有权利。
Two patients with causalgia associated with allodynia and finger contracture were treated surgically with a bioresorbable nerve guide tube made from polygycolic acid and collagen: the injured segment of the digital nerve was resected and the resulting gap (25 and 36 mm) was bridged with the tube. In both cases, a neuroma was found on the injured nerve and many sprouting branches were. After reconstruction, the causalgia and allodynia disappeared and movement of the fingers recovered during the following 6 months. Functional recovery was objectively identified for 1 year and 9 months. Both patients regained full use of their finger and were free of discomfort for up to 24 and 18 months, respectively. Since the first description of causalgia in 1864, there has been no definitive treatment for this intractable burning pain. Our experience shows that at least some types of causalgia can be resolved successfully by surgery. (c) 2005 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved.