ABO and Rh(D) phenotype frequencies of different racial/ethnic groups in the United States
ABO and Rh(D) phenotype frequencies of different racial/ethnic groups in the United States
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DOI：
10.1111/j.1537-2995.2004.03338.x
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发表时间：
2004-05-01
期刊：
影响因子：
2.9
通讯作者：
McEntire, R
中科院分区：
文献类型：
--
作者：
Garratty, G;Glynn, SA;McEntire, R
背景技术背景：在美国，通常引用的ABO/Rh（D）频率通常来自于相对较小的研究，其种族或民族类别通常通过姓名或外观来判断。一个10年的人口统计数据库，包含在美国5个血液中心献血的310万异基因和自体供体的种族或民族和ABO/Rh（D）表型数据，用于计算ABO和Rh（D）不同种族/民族的表型。种族或民族类别指定的donor.RESULTS：O组的最高百分比被发现在西班牙裔（56.5%），北美印第安人（54.6%），和黑人非西班牙裔（50.2%）捐助者。西班牙裔和黑人非西班牙裔供体的Rh-百分比（分别为7.3%和7.1%）远低于白色非西班牙裔供体（17.3%）。O型Rh-和B型Rh-多见白色非西班牙裔供体中（分别为8.0%和1.8%）高于西班牙裔供体（3.9%和0.7%），非西班牙裔黑人（3.6%和1.3%）和亚洲人（0.7%和0.4%）供体。这些数据证实，西班牙裔、亚裔和白色非西班牙裔供体中分别存在最高百分比的ORh+、BRh+/ABRh+和Rh-。这些是美国主要人种/种族供体组ABO/Rh（D）表型频率的最大和最准确的数据。
BACKGROUND: Commonly quoted ABO/Rh(D) frequencies in the US are usually from relatively small studies with racial or ethnic categories often judged by name or appearance.STUDY DESIGN AND METHODS: A 10-year demographic database that contained racial or ethnic and ABO/Rh(D) phenotype data on 3.1 million allogeneic and autologous donors giving blood at five blood centers in the US was used to compute ABO and Rh(D) phenotypes in various racial/ethnic groups. The racial or ethnic category was designated by the donor.RESULTS: The highest percentage of Group O was found in Hispanic (56.5%), North American Indian (54.6%), and black non-Hispanic (50.2%) donors. Hispanic and black non-Hispanic donors had a much lower percentage (7.3 and 7.1%, respectively) of Rh-compared to white non-Hispanic donors (17.3%). Group O Rh- and Group B Rh- were found more commonly (8.0 and 1.8%, respectively) in white non-Hispanic donors than in Hispanic (3.9 and 0.7%), black non-Hispanic (3.6 and 1.3%), and Asian (0.7 and 0.4%) donors.CONCLUSIONS: These data confirmed that the highest percentages of ORh+, BRh+/ABRh+, and Rh- are present in Hispanic, Asian, and white non-Hispanic donors, respectively. These are the largest and most accurate data of ABO/Rh(D) phenotype frequencies for the major racial/ethnic donor groups in the US.