Families of transmembrane sugar transport proteins
Families of transmembrane sugar transport proteins
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DOI：
10.1046/j.1365-2958.2000.01759.x
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发表时间：
2000-02-01
影响因子：
3.6
通讯作者：
Saier, MH
中科院分区：
文献类型：
--
作者：
Saier, MH
我们描述了20个次级(PMF驱动的)载体家族，除了依赖于ATP的ABC超家族中的9个家族和革兰氏阴性细菌外膜孔蛋白的7个家族外，它们主要负责糖及其衍生物的立体特异性运输进出地球上所有的活细胞。描述了家族特征以及家族成员的结构和功能特性。通过参考我们的网站(http://www-biology.ucsd.edu/similar to MSAIER/TRANSPORT/)，还可以获得系统发育关系、详细的底物专一性信息以及一级和二级参考文献。这篇综述提供了一个全面的指南，介绍了介导含糖分子跨细胞膜和细胞膜运输的载体的多样性。
We describe here 20 families of secondary (pmf-driven) carriers which, in addition to nine families within the ATP-dependent ABC superfamily, and seven families of Gram-negative bacterial outer membrane porins, largely account for the stereospecific transport of sugars and their derivatives into and out of all living cells on earth. Family characteristics as well as struc-tural and functional properties of the family constituents are described. By reference to our website (http://www-biology.ucsd.edu/similar to msaier/transport/), phylogenetic relationships, detailed substrate specificity information and both primary and secondary references are also available. This review provides a comprehensive guide to the diversity of carriers that mediate the transport of sugar-containing molecules across cell and organellar membranes.