Comparison of prognostic value of Roper Hall and Dua classification systems in acute ocular burns

Comparison of prognostic value of Roper Hall and Dua classification systems in acute ocular burns
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DOI:
10.1136/bjo.2009.173724
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发表时间:
2011-02-01
影响因子:
4.1
通讯作者:
Tandon, Radhika
Tandon, Radhika
中科院分区:
医学2区
文献类型:
--
作者:
Gupta, Noopur;Kalaivani, Mani;Tandon, Radhika

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目的比较两种不同的预后分类系统,即Dua和罗珀霍尔classification.Patients和方法在一个前瞻性的,随机的,对照的临床试验中,急性眼烧伤的程度在100例患者进行了分级罗珀霍尔和Dua分类的预测结果。患者被随机分为两组,每组50人,接受单独的常规药物治疗或额外的羊膜移植(AMT)。中度烧伤在两个系统下的分级相似(II级和III级),而重度烧伤的分类不同,并进一步比较。基线参数(上皮缺损大小、角膜混浊、角膜缘缺血、结膜受累和视力)和结局变量结果两组角膜上皮缺损的愈合时间和愈合率无明显差异,角膜透明度、角膜血管化、视力恢复和睑球粘连的发生率无明显差异。但IV级、V级和VI级之间角膜血管化程度有显著差异(p
Aim To compare the predictive outcome of ocular burns using two different prognostic classification systems, that is, Dua and Roper Hall classification.Patients and methods In a prospective, randomised, controlled clinical trial, the extent of acute ocular burns in 100 patients was graded by Roper Hall and Dua classifications. Patients were randomised in two groups of 50 each to receive conventional medical therapy alone or additional amniotic membrane transplantation (AMT). Moderate burns were graded similarly (grade II and III) under both systems, while severe burns were classified differently and compared further. Baseline parameters (size of epithelial defect, corneal haze, limbal ischaemia, conjunctival involvement and visual acuity) and outcome variables (healing of epithelial defect, corneal clarity, corneal vascularisation, visual outcome and symblepharon) after 1 year were noted and compared.Results There was no difference in terms of time taken and rate of healing of epithelial defect, but there was a significant difference in extent of corneal vascularisation between grades IV, V and VI (p